The calculated distance (air line) between Colonia Nicolich and Fray Bentos is approximately 176 miles respectively 283 kilometers.
By car or train, the actual journey to Fray Bentos is certainly longer, as only the direct route (as the crow flies) between Colonia Nicolich and Fray Bentos has been calculated here.
Air line (approximately)
283 kilometers
153 nautical miles