The calculated distance (air line) between Iztapalapa and Xalapa de Enríquez is approximately 140 miles respectively 226 kilometers.
By car or train, the actual journey to Xalapa de Enríquez is certainly longer, as only the direct route (as the crow flies) between Iztapalapa and Xalapa de Enríquez has been calculated here.
Air line (approximately)
226 kilometers
122 nautical miles