The calculated distance (air line) between San Miguel del Padrón and Güira de Melena is approximately 24 miles respectively 38 kilometers.
By car or train, the actual journey to Güira de Melena is certainly longer, as only the direct route (as the crow flies) between San Miguel del Padrón and Güira de Melena has been calculated here.
Air line (approximately)
38 kilometers
21 nautical miles