The calculated distance (air line) between Quemado de Güines and Guanabacoa is approximately 132 miles respectively 213 kilometers.
By car or train, the actual journey to Guanabacoa is certainly longer, as only the direct route (as the crow flies) between Quemado de Güines and Guanabacoa has been calculated here.
Air line (approximately)
213 kilometers
115 nautical miles