The calculated distance (air line) between San Mateo Ixtatán and Chiquimula is approximately 147 miles respectively 237 kilometers.
By car or train, the actual journey to Chiquimula is certainly longer, as only the direct route (as the crow flies) between San Mateo Ixtatán and Chiquimula has been calculated here.
Air line (approximately)
237 kilometers
128 nautical miles