The calculated distance (air line) between Santiaguito Tlalcilalcalli and Puebla is approximately 102 miles respectively 164 kilometers.
By car or train, the actual journey to Puebla is certainly longer, as only the direct route (as the crow flies) between Santiaguito Tlalcilalcalli and Puebla has been calculated here.
Air line (approximately)
164 kilometers
88 nautical miles