The calculated distance (air line) between Khān Shaykhūn and Ḩamāh is approximately 22 miles respectively 36 kilometers.
By car or train, the actual journey to Ḩamāh is certainly longer, as only the direct route (as the crow flies) between Khān Shaykhūn and Ḩamāh has been calculated here.
Air line (approximately)
36 kilometers
19 nautical miles