The calculated distance (air line) between Khān Shaykhūn and I‘zāz is approximately 82 miles respectively 132 kilometers.
By car or train, the actual journey to I‘zāz is certainly longer, as only the direct route (as the crow flies) between Khān Shaykhūn and I‘zāz has been calculated here.
Air line (approximately)
132 kilometers
71 nautical miles