The calculated distance (air line) between Ústí nad Orlicí and Karlovy Vary is approximately 157 miles respectively 253 kilometers.
By car or train, the actual journey to Karlovy Vary is certainly longer, as only the direct route (as the crow flies) between Ústí nad Orlicí and Karlovy Vary has been calculated here.
Air line (approximately)
253 kilometers
136 nautical miles