The calculated distance (air line) between Sezimovo Ústí and Prostějov is approximately 109 miles respectively 176 kilometers.
By car or train, the actual journey to Prostějov is certainly longer, as only the direct route (as the crow flies) between Sezimovo Ústí and Prostějov has been calculated here.
Air line (approximately)
176 kilometers
95 nautical miles