The calculated distance (air line) between Brandýs nad Labem-Stará Boleslav and Pilsen is approximately 65 miles respectively 104 kilometers.
By car or train, the actual journey to Pilsen is certainly longer, as only the direct route (as the crow flies) between Brandýs nad Labem-Stará Boleslav and Pilsen has been calculated here.
Air line (approximately)
104 kilometers
56 nautical miles