The calculated distance (air line) between Santo Domingo de Guzmán and Santiago de Querétaro is approximately 79 miles respectively 128 kilometers.
By car or train, the actual journey to Santiago de Querétaro is certainly longer, as only the direct route (as the crow flies) between Santo Domingo de Guzmán and Santiago de Querétaro has been calculated here.
Air line (approximately)
128 kilometers
69 nautical miles