The calculated distance (air line) between Velké Meziříčí and Prostějov is approximately 50 miles respectively 81 kilometers.
By car or train, the actual journey to Prostějov is certainly longer, as only the direct route (as the crow flies) between Velké Meziříčí and Prostějov has been calculated here.
Air line (approximately)
81 kilometers
43 nautical miles