The calculated distance (air line) between Velké Meziříčí and Pardubice is approximately 49 miles respectively 78 kilometers.
By car or train, the actual journey to Pardubice is certainly longer, as only the direct route (as the crow flies) between Velké Meziříčí and Pardubice has been calculated here.
Air line (approximately)
78 kilometers
42 nautical miles