The calculated distance (air line) between Velké Meziříčí and Chomutov is approximately 138 miles respectively 223 kilometers.
By car or train, the actual journey to Chomutov is certainly longer, as only the direct route (as the crow flies) between Velké Meziříčí and Chomutov has been calculated here.
Air line (approximately)
223 kilometers
120 nautical miles