The calculated distance (air line) between Topes de Collantes and La Habana Vieja is approximately 171 miles respectively 275 kilometers.
By car or train, the actual journey to La Habana Vieja is certainly longer, as only the direct route (as the crow flies) between Topes de Collantes and La Habana Vieja has been calculated here.
Air line (approximately)
275 kilometers
148 nautical miles