The calculated distance (air line) between Setauket-East Setauket and The Bronx is approximately 40 miles respectively 65 kilometers.
By car or train, the actual journey to The Bronx is certainly longer, as only the direct route (as the crow flies) between Setauket-East Setauket and The Bronx has been calculated here.
Air line (approximately)
65 kilometers
35 nautical miles