The calculated distance (air line) between Middelburg and 's-Hertogenbosch is approximately 74 miles respectively 119 kilometers.
By car or train, the actual journey to 's-Hertogenbosch is certainly longer, as only the direct route (as the crow flies) between Middelburg and 's-Hertogenbosch has been calculated here.
Air line (approximately)
119 kilometers
64 nautical miles