The calculated distance (air line) between Meppel and 's-Hertogenbosch is approximately 79 miles respectively 126 kilometers.
By car or train, the actual journey to 's-Hertogenbosch is certainly longer, as only the direct route (as the crow flies) between Meppel and 's-Hertogenbosch has been calculated here.
Air line (approximately)
126 kilometers
68 nautical miles