The calculated distance (air line) between Villanueva del Arzobispo and Cartagena is approximately 117 miles respectively 188 kilometers.
By car or train, the actual journey to Cartagena is certainly longer, as only the direct route (as the crow flies) between Villanueva del Arzobispo and Cartagena has been calculated here.
Air line (approximately)
188 kilometers
102 nautical miles