The calculated distance (air line) between Sevilla and Sanlúcar de Barrameda is approximately 47 miles respectively 75 kilometers.
By car or train, the actual journey to Sanlúcar de Barrameda is certainly longer, as only the direct route (as the crow flies) between Sevilla and Sanlúcar de Barrameda has been calculated here.
Air line (approximately)
75 kilometers
41 nautical miles