The calculated distance (air line) between San Isidro and Vega de San Mateo is approximately 63 miles respectively 101 kilometers.
By car or train, the actual journey to Vega de San Mateo is certainly longer, as only the direct route (as the crow flies) between San Isidro and Vega de San Mateo has been calculated here.
Air line (approximately)
101 kilometers
54 nautical miles