The calculated distance (air line) between La Matanza de Acentejo and San Isidro is approximately 27 miles respectively 43 kilometers.
By car or train, the actual journey to San Isidro is certainly longer, as only the direct route (as the crow flies) between La Matanza de Acentejo and San Isidro has been calculated here.
Air line (approximately)
43 kilometers
23 nautical miles