The calculated distance (air line) between Santo Domingo de la Calzada and Oviedo is approximately 160 miles respectively 257 kilometers.
By car or train, the actual journey to Oviedo is certainly longer, as only the direct route (as the crow flies) between Santo Domingo de la Calzada and Oviedo has been calculated here.
Air line (approximately)
257 kilometers
139 nautical miles