The calculated distance (air line) between San Isidro de Curuguaty and Itauguá is approximately 122 miles respectively 196 kilometers.
By car or train, the actual journey to Itauguá is certainly longer, as only the direct route (as the crow flies) between San Isidro de Curuguaty and Itauguá has been calculated here.
Air line (approximately)
196 kilometers
106 nautical miles