The calculated distance (air line) between San Isidro de Curuguaty and Caaguazú is approximately 72 miles respectively 116 kilometers.
By car or train, the actual journey to Caaguazú is certainly longer, as only the direct route (as the crow flies) between San Isidro de Curuguaty and Caaguazú has been calculated here.
Air line (approximately)
116 kilometers
62 nautical miles