The calculated distance (air line) between San Isidro de Curuguaty and Horqueta is approximately 116 miles respectively 187 kilometers.
By car or train, the actual journey to Horqueta is certainly longer, as only the direct route (as the crow flies) between San Isidro de Curuguaty and Horqueta has been calculated here.
Air line (approximately)
187 kilometers
101 nautical miles