The calculated distance (air line) between Eskişehir and Afyonkarahisar is approximately 70 miles respectively 113 kilometers.
By car or train, the actual journey to Afyonkarahisar is certainly longer, as only the direct route (as the crow flies) between Eskişehir and Afyonkarahisar has been calculated here.
Air line (approximately)
113 kilometers
61 nautical miles