The calculated distance (air line) between Senigallia and Reggio nell'Emilia is approximately 145 miles respectively 233 kilometers.
By car or train, the actual journey to Reggio nell'Emilia is certainly longer, as only the direct route (as the crow flies) between Senigallia and Reggio nell'Emilia has been calculated here.
Air line (approximately)
233 kilometers
126 nautical miles