The calculated distance (air line) between Osimo and Reggio nell'Emilia is approximately 164 miles respectively 265 kilometers.
By car or train, the actual journey to Reggio nell'Emilia is certainly longer, as only the direct route (as the crow flies) between Osimo and Reggio nell'Emilia has been calculated here.
Air line (approximately)
265 kilometers
143 nautical miles