The calculated distance (air line) between Orbetello and Reggio nell'Emilia is approximately 159 miles respectively 255 kilometers.
By car or train, the actual journey to Reggio nell'Emilia is certainly longer, as only the direct route (as the crow flies) between Orbetello and Reggio nell'Emilia has been calculated here.
Air line (approximately)
255 kilometers
138 nautical miles