The calculated distance (air line) between Luino and Reggio nell'Emilia is approximately 128 miles respectively 207 kilometers.
By car or train, the actual journey to Reggio nell'Emilia is certainly longer, as only the direct route (as the crow flies) between Luino and Reggio nell'Emilia has been calculated here.
Air line (approximately)
207 kilometers
112 nautical miles