The calculated distance (air line) between San Matías and San Ignacio de Velasco is approximately 170 miles respectively 274 kilometers.
By car or train, the actual journey to San Ignacio de Velasco is certainly longer, as only the direct route (as the crow flies) between San Matías and San Ignacio de Velasco has been calculated here.
Air line (approximately)
274 kilometers
148 nautical miles