The calculated distance (air line) between Casalecchio di Reno and Sassuolo is approximately 25 miles respectively 40 kilometers.
By car or train, the actual journey to Sassuolo is certainly longer, as only the direct route (as the crow flies) between Casalecchio di Reno and Sassuolo has been calculated here.
Air line (approximately)
40 kilometers
21 nautical miles