The calculated distance (air line) between Avignon and L'Isle-sur-la-Sorgue is approximately 12 miles respectively 20 kilometers.
By car or train, the actual journey to L'Isle-sur-la-Sorgue is certainly longer, as only the direct route (as the crow flies) between Avignon and L'Isle-sur-la-Sorgue has been calculated here.
Air line (approximately)
20 kilometers
11 nautical miles