The calculated distance (air line) between Thonon-les-Bains and Besançon is approximately 65 miles respectively 104 kilometers.
By car or train, the actual journey to Besançon is certainly longer, as only the direct route (as the crow flies) between Thonon-les-Bains and Besançon has been calculated here.
Air line (approximately)
104 kilometers
56 nautical miles