The calculated distance (air line) between Pont-Saint-Esprit and Villeurbanne is approximately 105 miles respectively 169 kilometers.
By car or train, the actual journey to Villeurbanne is certainly longer, as only the direct route (as the crow flies) between Pont-Saint-Esprit and Villeurbanne has been calculated here.
Air line (approximately)
169 kilometers
91 nautical miles