The calculated distance (air line) between Pernes-les-Fontaines and Villeurbanne is approximately 122 miles respectively 197 kilometers.
By car or train, the actual journey to Villeurbanne is certainly longer, as only the direct route (as the crow flies) between Pernes-les-Fontaines and Villeurbanne has been calculated here.
Air line (approximately)
197 kilometers
106 nautical miles