The calculated distance (air line) between Luxeuil-les-Bains and Villeurbanne is approximately 158 miles respectively 255 kilometers.
By car or train, the actual journey to Villeurbanne is certainly longer, as only the direct route (as the crow flies) between Luxeuil-les-Bains and Villeurbanne has been calculated here.
Air line (approximately)
255 kilometers
137 nautical miles