The calculated distance (air line) between Le Puy-Sainte-Réparade and Grenoble is approximately 106 miles respectively 170 kilometers.
By car or train, the actual journey to Grenoble is certainly longer, as only the direct route (as the crow flies) between Le Puy-Sainte-Réparade and Grenoble has been calculated here.
Air line (approximately)
170 kilometers
92 nautical miles