The calculated distance (air line) between Chalon-sur-Saône and Grenoble is approximately 118 miles respectively 190 kilometers.
By car or train, the actual journey to Grenoble is certainly longer, as only the direct route (as the crow flies) between Chalon-sur-Saône and Grenoble has been calculated here.
Air line (approximately)
190 kilometers
103 nautical miles