The calculated distance (air line) between Termas de Río Hondo and Santiago del Estero is approximately 42 miles respectively 68 kilometers.
By car or train, the actual journey to Santiago del Estero is certainly longer, as only the direct route (as the crow flies) between Termas de Río Hondo and Santiago del Estero has been calculated here.
Air line (approximately)
68 kilometers
37 nautical miles