The calculated distance (air line) between Villeneuve-lès-Avignon and Grenoble is approximately 95 miles respectively 153 kilometers.
By car or train, the actual journey to Grenoble is certainly longer, as only the direct route (as the crow flies) between Villeneuve-lès-Avignon and Grenoble has been calculated here.
Air line (approximately)
153 kilometers
83 nautical miles