The calculated distance (air line) between L'Isle-d'Abeau and Nîmes is approximately 130 miles respectively 210 kilometers.
By car or train, the actual journey to Nîmes is certainly longer, as only the direct route (as the crow flies) between L'Isle-d'Abeau and Nîmes has been calculated here.
Air line (approximately)
210 kilometers
113 nautical miles