The calculated distance (air line) between L'Isle-d'Abeau and Grenoble is approximately 39 miles respectively 62 kilometers.
By car or train, the actual journey to Grenoble is certainly longer, as only the direct route (as the crow flies) between L'Isle-d'Abeau and Grenoble has been calculated here.
Air line (approximately)
62 kilometers
34 nautical miles