The calculated distance (air line) between Ambérieu-en-Bugey and Grenoble is approximately 57 miles respectively 91 kilometers.
By car or train, the actual journey to Grenoble is certainly longer, as only the direct route (as the crow flies) between Ambérieu-en-Bugey and Grenoble has been calculated here.
Air line (approximately)
91 kilometers
49 nautical miles