The calculated distance (air line) between La Plata and San Nicolás de los Arroyos is approximately 169 miles respectively 273 kilometers.
By car or train, the actual journey to San Nicolás de los Arroyos is certainly longer, as only the direct route (as the crow flies) between La Plata and San Nicolás de los Arroyos has been calculated here.
Air line (approximately)
273 kilometers
147 nautical miles