The calculated distance (air line) between L'Isle-sur-la-Sorgue and Villeurbanne is approximately 128 miles respectively 206 kilometers.
By car or train, the actual journey to Villeurbanne is certainly longer, as only the direct route (as the crow flies) between L'Isle-sur-la-Sorgue and Villeurbanne has been calculated here.
Air line (approximately)
206 kilometers
111 nautical miles