The calculated distance (air line) between Vohburg an der Donau and Karlsruhe is approximately 147 miles respectively 236 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Vohburg an der Donau and Karlsruhe has been calculated here.
Air line (approximately)
236 kilometers
128 nautical miles