The calculated distance (air line) between Schwarzenbach an der Saale and Karlsruhe is approximately 179 miles respectively 288 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Schwarzenbach an der Saale and Karlsruhe has been calculated here.
Air line (approximately)
288 kilometers
155 nautical miles